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Technologies for health
The materials presented at the exhibition cover a wide range of issues in the field of medical biotechnology, cellular and genetic engineering, including the achievements of genetic engineering in the production of recombinant drugs, selective allergens and reagents for modern diagnostic methods. The publications reflect the results of research in the field of technology for obtaining new biomedical drugs, the prospects for the use of nanotechnology in the creation of new medicines are considered. An overview of current developments in biotechnological production in the field of vaccines, bacteriophages, bacterial preparations that normalize the human microflora, antibiotics, vitamins and enzyme preparations is given, their importance for human health is shown.
During the preparation of the exhibition, publications from the SPSTB Foundation of Russia were used: monographs, educational and methodological manuals, articles from specialized journals, collections of reports and conference materials, abstracts of dissertations, as well as publications from the Springer publishing house full-text database, articles from the electronic journals "Molecular Pharmaceuticals", "Biotechnology Progress", "Preparatory Biochemistry and Biotechnology", "Nature Methods". The materials of the exhibition can be useful to graduate students, students and teachers, as well as specialists working in the field of regenerative medicine, medical materials science, biotechnology, pharmaceuticals.
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Authorization is required to read electronic publications presented at the exhibition. Logins and passwords for authorization are placed in the Personal Account in the "Licensed resources" section.
Thematic sections of the exhibition:
2. Bioengineering technologies in medicine
3. Medications. Pharmaceutical biotechnology
1. Д10-19/74035
Актуальные проблемы химии, биологии и биотехнологии : материалы XII Всероссийской с международным участием научной конференции, 14-18 мая 2019 г. / Министерство науки и высшего образования Российской Федерации, Северо-Осетинский государственный университет имени Коста Левановича Хетагурова ; редакционная коллегия: Гаппоева В. С. (ответственный редактор). – Владикавказ : Изд-во Северо-Осететинского гос. ун-та им. К. Л. Хетагурова, 2019. – 273 с. : ил. – Парал. загл. ст., аннот. англ. – Библиогр. в конце ст. – ISBN 978-5-8336-1019-0. – Текст : непосредственный.
Abstract: The collection of articles includes materials of reports on topical issues of chemistry, biology and biotechnology presented at the XII All-Russian Scientific Conference with international participation, held in Vladikavkaz on May 14-18, 2019.
2. Д10-19/70968
Артюхова, С. И.
Биотехнология микроорганизмов: пробиотики, пребиотики, метабиотики : учебное пособие / С. И. Артюхова, О. В. Козлова ; Министерство науки и высшего образования Российской Федерации, Кемеровский государственный университет. – Кемерово : Кемеровский гос. ун-т, 2019. – 224 с. : ил. – Библиогр. : с. 192-214 (197 назв.). – Предм. указ. : с. 215-224. – ISBN 978-5-8353-2548-1. – Текст : непосредственный.
Abstract: The textbook was developed in the discipline "Industrial production of biologically active substances". The textbook presents data on microbial biotechnology, presents material on probiotics, their properties and the biotechnological potential of probiotic microorganisms, shows their importance for human health. Prebiotic compounds that selectively stimulate probiotic microorganisms and improve various physiological functions of the human body are described, metabiotics that contain metabolic products or structural components of probiotic microorganisms and are a new group of microecological agents aimed at preserving and restoring the functions of the human microbiome are considered.
3. Д9-08/62782
Биомедицина XXI века. Достижения и перспективные направления развития : сборник научных трудов / под редакцией Ю. А. Рахманина ; Российская академия естественных наук. – Москва : Изд. Рос. акад. естеств. наук, 2008. – 471 с. : ил. – Алф. указ.: с.470-471. – ISBN 978-5-94515-069-0. – Текст : непосредственный.
Abstract: Collection of scientific papers of the Biomedical Section of the Russian Academy of Sciences, devoted to theoretical, applied, methodological problems of biomedicine and healthcare in Russia, relevant at the beginning of the XXI century, analysis of the health status of the Russian population, experience in studying the influence of factors of anthropopression on human health and experience in health management.
4. Р2915
Биотехнология = Biotechnology : теоретический и научно-практический журнал / Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов национального исследовательского центра "Курчатовский институт" . – Москва : НИЦ "Курчат. ин-т" – ГосНИИгенетика, 1985 – (М.). – Перевод заглавия: Bioengineering. – В надзаг. : 1986-1992 М-во мед. и микробиол. пром-сти СССР. – До 1998 г. период.: ежемесячно . – Журн. вкл. в РИНЦ. – Выходит раз в два месяца. – ISSN 0234-2758.
Abstract: The journal publishes original articles related to various aspects of biotechnology that have practical applications in the fields of medicine, agriculture, environmental protection, modern industry and "green chemistry". Articles are published concerning both the creation of micro- and microorganisms with useful properties by methods of genetic engineering, classical breeding, high-performance screening, and original biotechnological processes, equipment, methods of product analysis and methods of process control.
5. Д10-20/72224
Биотехнология : учебник / В. А. Колодязная, Н. В. Котова, М. А. Самотруева [и др.] ; под редакцией В. А. Колодязной, М. А. Самотруевой. – Москва : ГЕОТАР-Медиа, 2020. – 382 с. : ил. + 6 л. ил. – (Учебник). – Авт. указ. на с. 5. – Библиогр. : с. 367-368. – Предм. указ. : с. 379-382 . – Факт. дата выхода кн. – 2019 г. – ISBN 978-5-9704-5436-7. – Текст : непосредственный.
Abstract: In the light of modern ideas, the book outlines the basics of industrial biotechnology, cellular and genetic engineering, and engineering enzymology. Special attention is paid to the processes of obtaining medicines by biotechnological methods. The production technologies of various classes of biologically active substances, such as antibiotics, therapeutic recombinant proteins, enzymes, vitamins, hormones, etc. are considered in detail.
6. Д8-02/79537
Биотехнология, экология, медицина : материалы III и IV международных научных семинаров 2001-2002 гг. / Под редредакцией А. Ф. Труфанова. – Москва ; Киров : Экспресс, 2002. – 149 с. – В надзаг. : Междунар. нау.-техн. центр, Гос. науч. учреждение "Волго-Вятский центр приклад. биотехнологии". – Библиогр. в конце отд. докл. – ISBN 5-88786-001-4. – Текст : непосредственный.
Abstract: The collection contains selected materials of reports read by the authors at the III and IV scientific and practical seminars held by the Volga-Vyatka Center for Applied Biotechnology under the auspices of the International Scientific and Technical Center in 2000-2002. The materials cover a wide range of issues in biotechnology, applied ecology and healthcare.
7. У4270/2014/56/1
Власов В. В.
Комплементарные здоровью прошлое, настоящее и будущее антисмысловых технологий / В. В. Власов, Д. В. Пышный, М. А. Зенкова, П. Е. Воробьев. – Текст : непосредственный // Наука из первых рук. – 2014. – № 1 (55). – С 38-49.
Abstract: In the early 1960s, Siberia became the "cradle" of a fundamentally new direction in molecular biology and pharmacology, which was far ahead of its time. The idea, implemented by a group of Novosibirsk researchers led by D. G. Knorre, was to create biologically active substances aimed directly at the genetic targets of DNA and RNA. Such substances were oligonucleotides fragments of nucleic acids capable of specifically binding to their complementary sequences. With the help of such "antisense" drugs, it became possible to suppress the reproduction of bacteria and viruses, as well as regulate the work of genes in cells of higher organisms, including in tumor cells. Nowadays, a large research and industrial sector of the economy is engaged in the development and synthesis of oligonucleotides and their modified analogues. Antiviral and anti-inflammatory drugs created on their basis are undergoing clinical trials, and some are already being used in medical practice. In particular, "at home" antisense technologies are developing drugs that effectively block genes responsible for drug resistance of cancer cells and pathogenic microorganisms.
8. Д9-12/92087
Клеточная биотехнология : учебное пособие / Г. П. Пинаев [и др.]. – Санкт-Петербург : Изд-во Политехн. ун-та, 2012. – 205 с. : ил. – Библиогр. : с. 200. – ISBN 978-5-7422-3630-6. – Текст : непосредственный.
Abstract: Modern knowledge about the main directions of cell biotechnology development, cell culture as the basis of cell technologies aimed at the development of methods and approaches of cell replacement therapy is presented. Methods of cell culture cultivation are described. The textbook contains a modern understanding of the biology of embryonic and somaticIt contains theoretical and applied questions of the courses "Biophysical foundations of living systems" and "Biophysics of ionizing radiation", as well as practical and computational and graphic material for students' self-study.
9. Д10-19/75464
Кузнецов, А. А.
Физические основы биомедицинских технологий : учебное пособие / А. А. Кузнецов ; Министерство науки и высшего образования Российской Федерации, Владимирский государственный университет имени Александра Григорьевича и Николая Григорьевича Столетовых. – Владимир : ВлГУ, 2019. – 127 с. : ил. – Библиогр. : с. 124 (13 назв.). – ISBN 978-5-9984-1036-9. – Текст : непосредственный.
Abstract: It contains theoretical and applied questions of the courses "Biophysical foundations of living systems" and "Biophysics of ionizing radiation", as well as practical and computational and graphic material for students' self-study.
10. Д8-01/72751
Международный симпозиум "Молекулярные механизмы генетических процессов и биотехнология" и сателлитный мини-симпозиум молодых ученых "Молекулярная генетика и биотехнология" / "Молекулярные механизмы генетических процессов и биотехнология", международный симп. (2001 ; Москва) . – Москва ; Минск : [б. и.], 2001. – 448 с. – В надзаг. : Рос. АН, Ин-т общ. генетики им. Н. И. Вавилова, Федерал. программа "Интеграция" и др. – Текст : непосредственный.
Abstract: Abstracts of the symposium "Molecular Mechanisms of genetic Processes and Biotechnology", held on November 18-21, 2001 in Moscow and November 22-24 in Minsk, in English. Organized by the Russian Academy of Sciences, the N. I. Vavilov Institute of General Genetics of the Russian Academy of Sciences, the Ministry of Industry, Science and Technology of the Russian Federation, etc. The conference was attended by leading experts in the field of genetics, molecular genetics and biotechnology. The Organizing Committee was headed by Academician of the Russian Academy of Sciences Yu. P. Altukhov, Academician of the National Academy of Sciences (Belarus) The N. A. Cartel.
11. Ж2-20/69062
Научный парк СПбГУ. Биомедицина, экология, природопользование : сборник / ответственные редакторы: К. В. Волков [и др.]. – Санкт-Петербург : Изд-во Санкт-Петербургского ун-та, 2020. – 162, [1] с. : ил. – Библиогр. в конце ст. – ISBN 978-5-288-06026-7. – Текст : непосредственный.
Abstract: The book is intended for specialists, and can also be used in educational programs for the preparation of students and postgraduates in the fields of ecology, biology and fundamental medicine.
12. Д10-05/10070
Парашин, В. Б.
Биомеханика кровообращения : учебное пособие / В. Б. Парашин, Г. П. Иткин ; под редакцией С. И. Щукина. – Москва : Изд-во МГТУ им. Н. Э. Баумана, 2005. – 223 с. : ил. – (Биомедицинская инженерия в техническом университете). – Библиогр. : с. 221- (16 назв.). – Текст : непосредственный.
Abstract: The classification of the main sections of modern biomechanics is given and their contents are briefly outlined. The necessity of in-depth study of blood circulation biomechanics in bioengineering training of technical university students is substantiated. Rheological properties of blood, biomechanics of vessels and heart, biomechanics of devices of auxiliary and artificial blood circulation are considered.
13. М/73961/4
Перспектива – 2018 : материалы международной научной конференции студентов, аспирантов и молодых учёных : [в 4 т.] / Министерство образования и науки Российской Федерации, Кабардино-Балкарский государственный университет им. Х. М. Бербекова ; редакционная коллегия Кумыков А. М. (ответсвенный редактор) [и др.]. – Нальчик : Кабардино-Балкарский гос. ун-т им. Х. М. Бербекова, 20 – . – Текст : непосредственный.
Т. 4 : Медицина. Физика и медицинская физика. Архитектура и дизайн. Журналистика. Филология. Математика. Информатика. – 2018. – 374 с. : ил. – Парал. загл. ст., аннот. англ. – Библиогр. в конце ст. – ISBN 978-5-7558-0606-0.
Abstract: Volume 4 contains reports on sections: "Journalism", "Philology", "Mathematics", "Computer Science", "Architecture and Design", "Medicine" and "Physics and Medical Physics". The collection publishes scientific reports of students, postgraduates and young scientists. The issues of scientific activity, new developments in the field of medical technology, biomedical research, biochemical research, architecture and design, mathematics and mathematical research, computer science and information technology, philology, journalism, physics are considered.
14. Д10-20/81755
Попова, О. В.
Тело как территория технологий от социальной инженерии к этике биотехнологического конструирования / О. В. Попова ; Российская академия наук, Институт философии. – Москва : Канон-плюс, 2020. – 335 с. – (Независимый альянс). – Библиогр. : с. 322-333 (235 назв.). – ISBN 978-5-88373-656-7. – Текст : непосредственный.
Abstract: In O. V. Popova's monograph "The body as the territory of technologies. From social engineering to the ethics of biotechnological design" presents a study of the problem of the human body in the context of the development of social and biomedical technologies. The logic of the research is due, firstly, to an attempt to problematize the concepts of "body", "physicality" in the history of philosophical thought, secondly, to consider the social and biotechnological construction of physicality in closed spaces: the army environment and concentration camps, on the territory of laboratories and intensive care units, thirdly, to explore the project of the body of an improved, enhanced Human enhancement technologies. The book is intended for a wide range of readers interested in modern social and ethical-philosophical problems of the development of science and technology.
15. Д9-07/34762
Сазыкин, Ю. О.
Биотехнология : учебное пособие / Ю. О. Сазыкин, С. Н. Орехов, И. И. Чакалева ; под редакцией А. В. Катлинского. – 2-е изд., стер. – Москва : Академия, 2007 (Тверь). – 254 с. – (Высшее профессиональное образование. Медицина). – Библиогр. : с. 250-251. – ISBN 978-5-7695-4040-0. – Текст : непосредственный.
Abstract: The main objects of biotechnology, ways of their creation and improvement by methods of cellular and genetic engineering, possibilities of intensification of biotechnological production by methods of engineering enzymology are considered. Special attention is paid to the problems of screening biotechnological drugs based on genomics, proteomics and bioinformatics data, prospects for combining biosynthesis and organic synthesis methods in the creation of new medicines. Information is given on the industrial production of amino acids, steroids, antibiotics, immunobiopreparations, enzymes of medical origin and other biotechnological preparations. A brief terminological dictionary is given.
16. Д10-19/69578
Селезнева, И. С.
Стандартизация и сертификаци в химической технологии и биотехнологии : учебное пособие / И. С. Селезнева, И. В. Гейде, М. А. Безматерных ; Министерство науки и высшего образования Российской Федерации, Уральский федеральный университет имени первого Президента России Б. Н. Ельцина, Химико-технологический институт. – Екатеринбург : Изд-во Уральского ун-та, 2019. – 203, [1] с. : ил. – Библиогр. : с. 136-139. – ISBN 978-5-7996-2623-5. – Текст : непосредственный.
Abstract: The textbook outlines the basics of the State Standardization System of the Russian Federation. Regulatory documents on quality, standardization and certification of raw materials, products of biotechnological industries, medicinal substances and biopolymers are analyzed. The issues of food safety are considered in accordance with the principles of HACCP, as well as certification of the food safety management system according to ISO and FSSC standards. Control questions, situational tasks and tests are offered. For students studying disciplines within the modules "Theory of technological processes and methods of control of organic synthesis products", "Quality management in biotechnological industries".
17. М/49478/12
Складнев, Д. А.
Что может биотехнология? / Д. А.Складнев. – Москва : Знание, 1990. – 47 с. : ил. – (Знак вопроса ; 12). – ISBN 5-07-001562-1. – Текст : непосредственный.
Abstract: In the brochure offered to your attention, the author - a professional biotechnologist - makes an attempt to explain the essence of the problems with which his science is dealing, to acquaint with its history, achievements, prospects using simple and understandable examples. Decoding genes, obtaining useful and necessary protein, creating medicines and vaccines that will help fight various ailments, developing new research tools, without which operations at the molecular level are simply unthinkable – all this is biotechnology.
18. Д8-03/92962
"Современное состояние российской биотехнологии", научно-практическая конференция (2003 ; Пущино) : материалы научно-практической конференции "Современное состояние российской биотехнологии", 28-29 окт. 2003 г. / "Современное состояние российской биотехнологии", научно-практическая конференция (2003 ; Пущино). – Москва : Златограф, 2003. – 55 с. – ISBN 5-93086-017-3. – Текст : непосредственный.
Abstract: The book contains materials (reports, abstracts) of the scientific and practical conference "The current state of Russian biotechnology", distributed under six thematic headings. The book is intended for technologists, biologists, doctors, agrobiologists, veterinarians, specialists in the field of industrial production of food products, medicines and medical devices.
19. Д10-16/41120
Учебно-методическое пособие по дисциплинам "Моделирование химико-технологических и биотехнологических процессов" / Санкт-Петербуржская государственная химико-фармацевтическая академия; составитель А. И. Мошинский [и др.]. – Санкт-Петербург : СПХФА, 2016. – 65 с. – Библиогр. : с. 65 (13 назв.). – ISBN 978-5-8085-0448-6. – Текст : непосредственный.
Abstract: The task of the training manual for the courses of modeling chemical-technological and biotechnological processes is to study in depth the main sections of the courses, consolidate the knowledge gained during the theoretical part of the courses, acquire practical skills of experimental research and the use of experimental data for engineering calculations. This manual is developed on the basis of methodological guidelines "Modeling and optimization of drug production processes"
20. Д10-20/84278
Химические и физико-химические методы исследования в медицине и биологии : учебное пособие по химии для самостоятельной работы студентов медико-биологических специальностей / А. В. Афанасьев, Е. В. Белова, К. Э. Герман [и др.] ; Министерство науки и высшего образования Российской Федерации, Институт физической химии и электрохимии имени А. Н. Фрумкина РАН [и др.]. – изд. 3-е, испр. и доп. – Москва : Граница, 2020. – 173 с. : ил. – Библиогр. : с. 172-173 (20 назв.). – ISBN 978-5-9933-0285-0. – Текст : непосредственный.
Abstract: This textbook is written in accordance with the content of State educational standards and the program of the discipline "Physico-chemical methods of analysis" in the specialty "Medicine", the direction and program of a large workshop (section "Physico-chemical methods of analysis"), which is performed by students in the specialty "Biology", "Biotechnology" It outlines the basics of physico-chemical methods of analysis. The conditions and areas of application of the methods, their advantages and disadvantages, limitations, development prospects and other features and characteristics are considered.
21. R/18177/100
Advances in biochemical engineering/ Biotechnology / ed. T. Scheper. – Berlin : Springer, 19 – . – ISSN 0724-6145. – Текст : непосредственный.
100 : Biotechnology for the future / ed. J. Nielsen; with contributions by S. Arnold, M. A. Asadollahi, U. T. Bornscheuer, J. Maury, K. Moller [et al.]. – Berlin, 2005. – XII, 229 p. : ill. – Библиогр. в конце ст. – Указ. : с. 205-229. – ISBN 3-540-25906-6.
Abstract: Covers trends in modern biotechnology. All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science, are treated.
22. Amit Kumar
Biotechnology and Bioforensics. New Trends / Amit Kumar. – Electronic text data. – Singapore : Springer, 2015. – 187 p. – (SpringerBriefs in Applied Sciences and Technology. Forensic and Medical Bioinformatics, ISSN 2191-5318). – ISBN 978-981-287-050-6. – DOI 10.1007/978-981-287-050-6. – URL: https://link.springer.com/book/10.1007/978-981-287-050-6#authorsandaffiliationsbook (дата обращения 26.11.2012). – Access mode : for authorization. users.
Abstract: This Brief covers broad areas of Applied Biology specifically into the domains of Biotechnology/Biomedicine and Forensic Science. Chapters included here would also explain the role of bioinformatics in protein and gene characterization, modeling of the protein structure, survey related to the chromosomal effect on Human Disorders like Diabetes and Cardiac Problems. This Brief is full of Innovative Literature like Use of Microbes in Electricity Production, Brain connection to Type 2 Diabetes etc. Interesting issues in Forensic biology and the aspects of Bioforensics like STR profiling of exhumed bones makes this brief truly useful and informative for Researchers. It also includes the advancements and new ideologies in understanding crop improvements & crop quality. This Brief witnesses Innovative Research related to the Bio and Agri software development too which are capable of accelerating Insilico biological data analysis.
23. Biomedical Technology / ed.: T. Lenarz, P. Wriggers. – Electronic text data. – Cham : Springer, 2015. – (Lecture Notes in Applied and Computational Mechanics, ISSN 1860-0816 ; vol. 74). – ISBN 978-3-319-10981-7. – DOI 10.1007/978-3-319-10981-7. – URL: https://link.springer.com/book/10.1007/978-3-319-10981-7 (дата обращения 26.11.2021). – Access mode : for authorization. users.
Abstract: This book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and challenges. The first part focuses on the virtual environment used to study biological systems at different scales and under multiphysics conditions. In turn, the second part is devoted to modeling and computational approaches in the field of cardiovascular medicine, e.g. simulation of turbulence in cardiovascular flow, modeling of artificial textile-reinforced heart valves, and new strategies for reducing the computational cost in the fluid-structure interaction modeling of hemodynamics. The book’s last three parts address experimental observations, numerical tests, computational simulations, and multiscale modeling approaches to dentistry, orthopedics and otology. Written by leading experts, the book reflects the remarkable advances that have been made in the field of medicine, the life sciences, engineering and computational mechanics over the past decade, and summarizes essential tools and methods (such as virtual prototyping of medical devices, advances in medical imaging, high-performance computing and new experimental test devices) to enhance medical decision-making processes and refine implant design. The contents build upon the International Conference on Biomedical Technology 2015 (ICTB 2015), the second ECCOMAS thematic conference on Biomedical Engineering, held in Hannover, Germany in October 2015.
24. R/10998/2006
Deutsche Gesellschaft fur chemische Technik und Biotechnologie ( Frankfurt am Mein).
Tatigkeitsbericht : материал технической информации / Dt. Ges. fur chem. Technik und Biotechnologie. – Frankfurt am Main : DECHEMA, 19 – . – Текст : непосредственный.
2006. – 2006. – 144 p. : ill.
25. G2/22509
Gotzen, S.
Biohybrid catalysts for selective transformations : dissertation / S. Gotzen ; Von der Fakultät für Mathematik, Informatik und Naturwissenschaften der RWTH Aachen University. – Aachen : [s. n.], 2016. – 117 p. : ill. – Библиогр. в конце разд. – Текст : непосредственный.
Abstract: The work delineated here was carried out between October 2010 and August 2014 in the Laboratories of Prof. Dr. Jun Okuda at the Institute of Inorganic Chemistry at RWTH Aachen University, Germany.
26. Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012) : Conference proceedings. Vol. 1 / ed. T. – C. Zhang [et al.]. – Electronic text data. – Berlin ; Heidelberg : Springer, 2014. – 645 p. – (Lecture Notes in Electrical Engineering, ISSN 1876-1119 ; vol. 249). – ISBN 978-3-642-37916-1. – URL: https://link.springer.com/book/10.1007/978-3-642-37916-1#editorsandaffiliations (дата обращения 26.11.2021). – Access mode : for authorization. users.
Abstract: The 2012 International Conference on Applied Biotechnology (ICAB 2012) was held in Tianjin, China on October 18-19, 2012. It provides not only a platform for domestic and foreign researchers to exchange their ideas and experiences with the application-oriented research of biotechnology, but also an opportunity to promote the development and prosperity of the biotechnology industry. The proceedings of ICAB 2012 mainly focus on the world's latest scientific research and techniques in applied biotechnology, including Industrial Microbial Technology, Food Biotechnology, Pharmaceutical Biotechnology, Environmental Biotechnology, Marine Biotechnology, Agricultural Biotechnology, Biological Materials and Bio-energy Technology, Advances in Biotechnology, and Future Trends in Biotechnology. These proceedings are intended for scientists and researchers engaging in applied biotechnology.
27. J2/27887
Mahfouf, M.
Intelligent systems modeling and decision support in bioengineering / M. Mahfouf. – Norwood, Ma : Artech house, 2006. – XII, 342 p. : ill. – (The Artech house engineering in medicine & biology series). – Библиогр. в конце частей. – Указ. : с. 337-342. – ISBN 1-58053-998-X. – Текст : непосредственный.
Abstract: Intelligent systems try to achieve, through the use of computers, what we associate with intelligence – flexible, learning and adaptive activity like we find in the human brain. For the first time, this groundbreaking resource provides a detailed understanding of the analysis, design, and application of new intelligent systems in the biomedical industry. The book covers the three major areas of application in biomedicine, including the modeling and control in human anaesthesia, decision support for critically ill patients in intensive care units, and modeling of humans who are subjected to physiological stress. The culmination of more than 18 years of research, this cutting-edge reference offers practical modeling and control guidance by presenting a combination of simulations, real-time experiments, and actual patient data.
28. J2/28951
Manual of industrial microbiology and biotechnology : conference proceedings / editors in chief R. H. Baltz [et al.] ; editors A. T. Bull [et. al.]. – 3 rd ed. – Washington, DC : ASM press, 2010. – XVIII, 766 p. : ill. – Библиогр. в конце ст. – Авт. указ. : с. -745-766. – ISBN 978-1-55581-512-7. – Текст : непосредственный.
Abstract: Reviews of the latest methods, approaches and options for the use of microorganisms and other cell culture systems for the production of pharmaceuticals, industrial enzymes and proteins, food and beverages, fuels and fine chemicals and other products. The main attention is paid to the latest achievements and conclusions about the current state of science and technology and contains a new section devoted to microbial production of biofuels and fine chemicals, as well as increased attention to methods of mammalian cell cultivation. It covers new methods that increase the capacity of microbes used for a wide range of purposes, from winemaking to pharmaceuticals to bioremediation, in volumes from micro to industrial scale.
29. R/18177/96/1
Marine Biotechnology : сборник научных трудов. – Berlin [etc.] : Springer, 20 – . – Текст : непосредственный.
1 / ed.: Y. Le Gal, R. Ulber; with contributions by G. Antranikian, S. Barindra, G. Barnathan, J.-P. Berge, C. Bertoldo [et al.]. – Berlin[etc.] : Springer, 2005. – X, 287 p. : ill. – (Advances in biochemical engineering/ Biotechnology / ed.: T. Scheper, ISSN 0724-6145 ; 96). – Библиогр. в конце ст. – Указ. : с. 263-287. – ISBN 3-540-25659-8.
Abstract: Marine biotechnology is an innovative field of research in science and technology concerning the support of living organisms with marine products and tools. To understand the omics of the living species: it is a novel way to produce genetically modified food, drugs, and energy to overcome global demand. The exploitation of biotechnology for drug discovery, including enzymes, antibiotics, and biopolymers, chemical compounds from marine sources are deliberated in this book. The concepts of marine microbiology and molecular biology are explored extensively in the present book. Biomedical applications of marine biomaterials such as tissue engineering, drug delivery, gene delivery, and biosensor areas are thoroughly discussed. Bioenergy from marine sources is a groundbreaking achievement in the field of marine biotechnology and is also covered in this book. Finally, industrial uses of marine-derived products are explored for mankind.
30. vr=P615909
Preparative Biochemistry and Biotechnology. – Electronic text data. – London [etc.] : Taylor & Francis group, 1971 – . – on-line. – Выходит 8 раз в год. – ISSN 1532-2297. – Режим доступа : http://www.tandfonline.com/toc/lpbb20/current (дата обращения 26.11.21). – Access mode : for authorization. users.
Abstract: Articles on the results of research related to all aspects of the development and application of preparative methods in biochemistry, biotechnology and other life sciences (on a laboratory, pilot and production scale), including synthetic methods, separation, isolation and purification of materials of biochemical and biotechnological significance, the use of nanoparticles. The research topics also cover pharmaceuticals, molecular and cellular biology, agrochemistry, natural products, genetic engineering, bioengineering, fermentation chemistry, cloning, stem cells, etc.
31. The third international conference on the development of biomedical engineering in Vietnam : BME2010, 11–14 January, 2010, Ho Chi Minh City, Vietnam / ed. V. Toi, T. Q. Khoa. – Electronic text data. – Berlin ; Heidelberg : Springer, 2010. – 319 p. – (IFMBE proceedings, ISSN 1680-0737 ; 27). – ISBN 978-3-642-12020-6. – URL: http://dx.doi.org/10.1007/978-3-642-12020-6 (дата обращения 26.11.21). – Access mode : for authorization. users.
Abstract: The Third International Conference on the Development of Biomedical Engineering in Vietnam was organized on January 11-14, 2010, by IU in Ho Chi Minh City, Vietnam and had the theme of: “New frontiers in Biomedical Engineering”. It reflected the steady growth of the activities in this field in Vietnam, and featured the contributions of researchers of 21 countries, including: Australia, Belgium, Canada, Denmark, France, India, Japan, Korea, Malaysia, New Zealand, Philippines, Poland, Russia, Singapore, Spain, Switzerland, Taiwan, Thailand, United Kingdom, the United States and Vietnam. Besides the invited, oral and poster presentations there were tutorial lectures to educate junior researchers in different subfields of Biomedical Engineering. This volume summarizes those presentations and was provided as an education foundation and scientific reference.
Bioengineering technologies in medicine
32. У4598
Актуальная биотехнология : журнал/ "Биоактуаль", о-во с ограниченной ответственностью. – Воронеж, 2012 – (Воронеж). – До 2018 г. изд-во: ВГУИТ. – Выходит ежеквартально. – ISSN 2304-4691. – Текст : непосредственный.
Аннотация: All areas of biotechnology, information technology and mathematical modeling, ecology and resource conservation, economics and management, pedagogy.
33. Д9-10/71076
Бабкина, С. С.
Биоаффинные методы анализа на основе ДНК / С. С. Бабкина, Н. А. Улахович, Ю. А. Бабкин. – Москва : МГОУ, 2010 (М.). – 193 с. : ил. – Библиогр. : с. 146-193 (323 назв.). – ISBN 978-5-7045-0965-3. – Текст : непосредственный.
Abstract: Electrochemical DNA sensors and bioaffinity methods based on DNA make it possible to study the interaction with DNA and determine antitumor pharmaceuticals of various mechanisms of action: preparations based on Pt(II) and Pt(IV) complexes forming covalent bonds with nucleotides; metallointercalators; intercalators of plant origin - alkaloids; antitumor antibiotics of the anthracycline group and others. It is possible to quantify the effect of antitumor drugs on the structure and functions of DNA, to establish the composition and stability of the resulting complexes. The use of modern nanomaterials in the described methods of analysis is considered. DNA-based bioaffinity methods provide the determination of pharmaceuticals without prior separation of components with high sensitivity and selectivity, as well as the assessment of the biological activity of new compounds in relation to DNA. Methods for the determination of low- and high-molecular biologically active substances that are DNA effectors are described.
34. Ж2-08/43988
Безбородов, А. М.
Ферментативные процессы в биотехнологии / А. М. Безбородов, Н. А. Загустина, В. О. Попов. – Москва : Наука, 2008 (СПб.). – 335 с. – Библиогр. в конце глав. – В надзаг. : Рос. АН, Ин-т биохимии им. А. Н. Баха. – ISBN 978-5-02-035661-0. – Текст : непосредственный.
Abstract: The monograph consists of three parts: microbiological synthesis, extreme forms of microorganisms in biotechnology, enzymatic reactions in biotechnology. The basic principles of the processes of regulation of metabolism in microorganisms, in particular, in the processes of microbiological synthesis during fermentation, are described. The material on the production of unconventional fermentation products is presented, the processes of microbiological synthesis by extreme forms of microorganisms (thermonuclei, psychrophiles, halophiles, alkalophiles) are described, as well as the production of metabolites using enzymes isolated from extreme forms. The third part presents the information necessary for biotechnologists about metabolic engineering and methods of enzyme stabilization. The description of organic synthesis reactions in organic solvents catalyzed by enzymes is given. Numerous examples of such reactions are given. The monograph concludes with a chapter in which the material on the current state of industrial biocatalysis is presented. For specialists working in the field of biotechnology, students, postgraduates and teachers of universities of biotechnological profile.
35. Д7-90/79128
Бекер, М. Е.
Биотехнология / М. Е. Бекер; М. Е. Бекер, Г. К. Лиепиньш, Е. П. Райпулис. – Москва : Агропромиздат, 1990. – 334 с. : ил. – Библиогр. : с. 312-313. – ISBN 5-10-001872-0. – Текст : непосредственный.
Abstract: The book is devoted to the achievements and problems of biotechnology. The basics of microbial synthesis, selection of producers of biologically active substances, genetic engineering, cellular engineering, cultivation of cells and tissues of multicellular organisms, principles of cell and enzyme immobilization are described in a popular, but at the same time at a high scientific level. Enough attention is paid to ecology. With the help of images in an electron microscope, changes in the internal structure of cells are shown depending on the conditions of cultivation.
36. М/71969/3
Биофизические и биохимические методы экспериментальной нейробиологии: современные представления = Biophysical and biochemical methods of experimental neurobiology: modern concepts : учебное пособие : [в 3 ч.] / Министерство науки и высшего образования Российской Федерации, Санкт-Петербургский политехнический университет Петра Великого, Институт биомедицинских систем и биотехнологий (Политех). – Санкт-Петербург : ПОЛИТЕХ-ПРЕСС, 2017 – . – Парал. тит. л. англ. – ISBN 978-5-7422-5898-8. – Текст : непосредственный.
Ч. 3 : В. А. Жемков, А. А. Болгов, О. Л. Власова, И. Б. Беспрозванный. – 2020. – 99 с. : ил. – Авт. указ. на обороте тит. л. – Библиогр. : с. 98-99. – ISBN 978-5-7422-7061-4. – DOI 110.18720/SPBPU/2/id20-186.
Abstract: The main methods of laboratory and practical medicine, biophysical research in experimental neurobiology and medicine used in laboratory practice as areas of applied and fundamental nature are described. Special attention in part 3 of the manual is paid to the methods of X-ray structural analysis of proteins, including neuronal, and the results of their interaction with ligands.
37. У4270/2016/70/4
Власов В. В.
Правда о фаготерапии, или памятка врачу и пациенту / В. В. Власов, П. Е. Воробьев, Д. В. Пышный. – Текст : непосредственный // Наука из первых рук. – 2016. – Т. 70, № 4. – С. 58-65.
Abstract: The first clinical experiments with bacterial viruses began almost a century ago - almost immediately after their discovery. It seemed that this new method of therapy was doomed to success: it was flawless from a scientific point of view, and the results of its application were promising. However, fragmentary knowledge of the biology of viruses and the lack of key molecular technologies in those distant years did not allow us to fully unlock the therapeutic potential of organisms that are not visible even in a light microscope. With the advent of antibiotics, interest in phage therapy, especially in Western countries, was almost lost. Why, in recent decades, have the world started talking about medical bacteriophages again? Why is it that the wonderful idea of using their natural enemies to destroy pathogenic bacteria has not yet been fully implemented? Both practitioners and their patients today should clearly understand not only the essence, but also all the strengths and weaknesses of this type of therapy, which has every chance to become part of the personalized medicine of the future.
38. У4270/2014/56/2
Власов В. В.
«Редакторы» геномов. От «цинковых пальцев» до CRISPR / В. В. Власов, С. М. Закиян, С. П. Медведев. – Текст : непосредственный // Наука из первых рук. – 2014. – Т. 56, № 2. – С. 44-53.
Abstract: The emergence of methods of manipulating genetic material marked a real revolution in biology, biotechnology and medicine. Targeted intervention in the genome of living organisms has allowed solving a wide range of tasks, ranging from the creation of modified species of bacteria, plants and animals with new valuable properties, and cellular models necessary for the creation of new drugs, to the development of gene therapy methods that open up prospects for correcting congenital genetic disorders. But in order to successfully invade the "holy of holies" of a cell – its hereditary material, technologies are needed that allow splitting and connecting DNA molecules in given areas. Truly, a revolutionary breakthrough in this field occurred only a few years ago, when a simple method of genetic engineering CRISPR/Cas was developed based on the mechanisms of "bacterial immunity", providing an accurate effect on the specified DNA sites. This method has opened up fundamentally new possibilities for manipulations at the genome level of higher organisms, allowing point mutations to be introduced, corrected, embedded or deleted fragments and even whole genes.
39. Ар18-9471
Денисенко, Ю. А.
Белковая инженерия грибных ксиланаз 10-й семьи гликозидгидролаз : специальность 03.01.04, 03.01.06 : автореферат диссертации на соискание ученой степени кандидата химических наук : / Ю. А. Денисенко ; Московский государственный университет имени М. В. Ломоносова. – Москва, 2018. – 26 с. : ил. – Библиогр. : с. 24-26. – Текст : непосредственный.
40. Ж2-07/41833
Ермилова, Е. В.
Молекулярные аспекты адаптации прокариот / Е. В. Ермилова. – Санкт-Петербург : Изд-во С.-Петерб. ун-та, 2007 (СПб.). – 298 с. – Библиогр. : с. 273-296. – В надзаг. : С.-Петерб. гос. ун-т. – ISBN 978-5-288-04288-1. – Текст : непосредственный.
Abstract: The monograph discusses the mechanisms and principles of regulation of the main molecular genetic processes on the example of adaptation of prokaryotes to the lack or absence of nutritional components and the action of the main physico-chemical factors characterizing the conditions of their habitat.
41. Ар20-3695
Ибатуллина, М. Р.
Супрамолекулярные системы на основе комплексов алкилированных производных 1,4-диазабицикло[2.2.2]октана и метилглюкамина с переходными металлами. Самоорганизация и функциональная активность : специальность 02.00.04 – Физическая химия : автореферат диссертации на соискание ученой степени кандидата химических наук / Ибатуллина Марина Рафаиловна. – Казань, 2020. – 24 с. : ил. – Библиогр. : с. 22-24 (27 назв.). – Текст : непосредственный.
42. Д8-02/75867
Исследование эмбриотоксической активности химических веществ : конспект лекций / Автор-составитель: А. С. Радилов, Е. Е. Ермолаева, Н. А. Чеботарь [и др.]. – Чебоксары : [б. и.], 2002. – 31 с. : ил. – Сост. указ. на обороте тит. л. – В надзаг. :Чуваш. ун-т им. И. Н. Ульянова. – Библиогр. : с. 30-31. – Текст : непосредственный.
Abstract: The methods of studying the embryotoxic effect of chemicals are described in detail.
43. Д9-04/7046
Калинин, В. Л.
Основы репликации : курс лекций / В. Л. Калинин. – Гатчина : ИПО ПИЯФ, 2004. – 124 с. : ил. – Библиогр. : с. 123-124 (27 назв.). – В надзаг. : Петерб. ин-т ядер. физики им. Б. П. Константинова РАН. – Текст : непосредственный.
Abstract: The publication discusses the key enzymes that carry out DNA biosynthesis. Auxiliary proteins involved in the first stages of replication are described. Special attention is paid to the mechanisms of replication initiation in bacterial and eukaryotic cells.
44. Д8-98/75741
Новые направления биотехнологии : тезисы докладов 8 конференции «Новые направления биотехнологии», 27-29 апреля 1998 г. – Москва : [б. и.], 1998. – 123 с. – В надзаг. : Рос. АН, Научный совет РАН по проблемам биотехнологии, Центр "Биоинженерия" РАН, Моск. мед. акад. им. И. М. Сеченова, Информ. центр по биотехнологии. – Текст : непосредственный.
Abstract: The VIII conference "New Directions of Biotechnology" is devoted to the consideration of the latest achievements and prospects for the development of such important areas of modern biotechnology as molecular agrobiotechnology, protein engineering, molecular medicine, as well as the problems of regulating the introduction of genetic engineering products into the environment and issues of legal support for work in the field of genetic engineering.
45. Д10-17/50540
Писарев, О. А.
Фракционирование биологически активных веществ. Аналитические и препаративные методы : учебное пособие / О. А. Писарев, И. В. Полякова ; Санкт-Петербургский политехнический университет Петра Великого. – Санкт-Петербург : Изд-во Политехн. ун-та, 2017. – 191 с. : ил. – Библиогр. : с. 190-191 (19 назв.). – ISBN 978-5-7422-5961-9. – Текст : непосредственный.
Abstract: The physico-chemical bases of the most important analytical and preparative processes of obtaining and fractionating biologically active substances are considered: high-performance liquid chromatography, extrusion chromatography, electrophoresis of preparative chromatography, affinity chromatography, non-sorption methods of isolation and purification.
46. Н/17948/2
Проблемы и перспективы молекулярной генетики : в 2-х томах / ответственный редактор Е. Д. Свердлов. – Москва : Наука, 20 – . – Текст : непосредственный.
Т. 2. – 2004. – 330 с. : ил. – Библиогр. в конце отд. ст. – ISBN 5-02-033657-2.
Abstract: The collection of articles covers a wide range of problems of modern molecular genetics, from structural aspects of carriers of genetic information to the human genome, embryonic stem cells and bioinformatics. The collection reflects the scientific achievements of the Institute of Molecular Genetics of the Russian Academy of Sciences in recent years
47. Ж2-00/29610
Саминский, Е. М.
Трансляция генетического кода на рибосомах / Е. М. Саминский. – Санкт-Петербург : Изд-во СПбГТУ, 2000. – 88 с. : ил. – В надзаг. : С.-Петерб. гос. техн. ун-т. – Библиогр. в конце разд. – Текст : непосредственный.
Abstract: The course of lectures delivered at the Department of Biophysics of the Faculty of Physics and Mechanics of St. Petersburg State Technical University in 1997-1999 is presented. It includes a brief history of decoding the genetic code; the structures and functions of ribosomes, ribosomal and transport RNAs, the processes of initiation, elongation and termination of code translation on ribosomes, as well as some issues of translation accuracy and cases of deviations from the standard rules for reading the genetic code are also considered.
48. Ар18-3422
Смолко, В. А.
Электрохимические сенсоры и ДНК-сенсоры на основе пиллар[5]арена и его производных : специальность 02.00.02 : автореферат диссертации на соискание ученой степени кандидата химических наук : / В. А. Смолко. – Казань, 2018. – 23 с. : ил. – Библиогр. : с. 23 (9 назв.). – Текст : непосредственный.
49. Д9-12/91576
Современные биоинженерные и ядерно-физические технологии в медицине : сборник материалов Международной молодежной научной школы, в рамках фестиваля науки (мероприятие 2.1 "Организация и проведение Всерос. и Междунар. молодеж. науч. конф. и шк." федерал. целевой программы "Науч. и науч.-пед. кадры инновац. России" на 2009-2013 г.); (Гос. контракт 14.741.11.0367 от 28.08.2012 г.) / Саратовский гос. технический ун-т им. Ю. А. Гагарина. – Саратов : Науч. кн., 2012. – 247 с. – Библиогр. в конце отд. ст. – В надзаг. : Саратов. гос. техн. ун-т им. Гагарина Ю. А. – ISBN 978-5-9758-1417-3. – Текст : непосредственный.
Abstract: The collection presents the materials of the International Youth Scientific School "Modern Bioengineering and Nuclear Physics technologies in medicine" within the framework of event 2.1 "Organization and holding of All-Russian and International youth scientific conferences and schools" of the federal target program "Scientific and pedagogical personnel of innovative Russia" for 2009-2013, held on September 18, 2012 at the Saratov State Technical University named after Gagarin Yu. A. in accordance with the order of the State Technical University No. 683-P dated 31.08.2012. The main objectives of the youth scientific school and the competition within its framework were to create conditions for the effective reproduction of scientific and scientific-pedagogical personnel and the consolidation of youth in the field of science, education and high technology; to preserve the continuity of generations in science and education by improving the quality of scientific and scientific-pedagogical personnel; effective motivation of youth research activities; creation of a system to stimulate the influx of youth into the field of science, education and high technology; expansion of relations between subjects of scientific and educational activities, as well as between the sectors of science, education and high technologies; activation of mechanisms for the integration of science and education.
50. Д9-06/26312
Спивак, И. М.
Экология. Повреждение и репарация ДНК : учебное пособие / И. М. Спивак. – Санкт-Петербург : Изд-во Политехн. ун-та, 2006. – 184 с. – Библиогр. : с. 181. – В надзаг. : С.-Петерб. гос. политехн. ун-т. – ISBN 5-7422-1218-6. – Текст : непосредственный.
Abstract: The manual describes the problems of DNA damage and repair. The modern concepts of the development of the global cell response to DNA damage are presented and the mechanisms responsible for maintaining the genetic stability of organisms are considered. The main attention is paid to the analysis of the relationship and interdependence of the three RNAs of DNA metabolism: replication, recombination and repair, including biochemistry, genetics and the evolution of these processes.
51. М/52492/1
Субетто, А. И.
Системогенетика и теория циклов / А. И. Субетто. – Санкт-Петербург, Москва : [б. и.], 19 – . – Текст : непосредственный.
Ч. 1. – 1994. – 243 с. : ил. – Труды Исследовательского центра. – Библиогр. : с. 226-240 (126 назв.).
Abstract: The monograph is a theoretical dilogy: systemogenetics and cycle theory. Systemogenetics, which makes up the first part of the book, reveals the content, structure, thesaurus, and basic laws of systemogenetics. Its interpretation is given in relation to technogenetics and design. The theory of cycles - the second part - is the theory of the life cycles of anthropogenic systems. The "exchange" concept of the theory of cycles is revealed on the basis of ideas about the resource spectrum, chronospectrum and effect spectrum. The basic laws in relation to the development of technical systems are systematized. In the same part, examples are given that develop the position of systemogenetics and the theory of cycles in relation to economic systems.
52. М/52492/2
Субетто, А. И.
Системогенетика и теория циклов / А. И. Субетто. – Санкт-Петербург, Москва : [б. и.], 19 – . – Текст : непосредственный.
Ч. 2. – 1994. – 260 с. : ил. – Труды Исследовательского центра / Исслед. центр пробл. качества подгот. специалистов. – Библиогр.в конце разд.
Abstract: The monograph is a theoretical dilogy: systemogenetics and cycle theory. Systemogenetics, which makes up the first part of the book, reveals the content, structure, thesaurus, and basic laws of systemogenetics. Its interpretation is given in relation to technogenetics and design. The theory of cycles - the second part - is the theory of the life cycles of anthropogenic systems. The "exchange" concept of the theory of cycles is revealed on the basis of ideas about the resource spectrum, chronospectrum and effect spectrum. The basic laws in relation to the development of technical systems are systematized. In the same part, examples are given that develop the position of systemogenetics and the theory of cycles in relation to economic systems.
53. Ар15-1916
Тевяшова, А. Н.
Разработка направленной модификации и анализ связи структура-активность полифункциональных антибиотиков-гликозидов : специальность 02.00.10 : автореферат диссертации на соискание ученой степени доктора химических наук : / А. Н. Тевяшова. – Москва, 2015. – 45 с. : ил. – Библиогр. : с. 41-45 (55 назв.). – Текст : непосредственный.
54. Ж2-16/60581
Тканевая инженерия и клеточные технологии с использованием пористо-проницаемых инкубаторов из никелида титана / О. В. Кокорев [и др.] ; под редакцией В. Э. Гюнтера ; Сибирский государственный медицинский университет [и др.]. – Томск : МИЦ, 2016. – 149 с. : ил. – Авт. указ. на обороте тит. л. – Библиогр. : с. 141-149 (150 назв.). – ISBN 978-5-98589-059-4. – Текст : непосредственный.
Abstract: The book presents the problems of tissue engineering and prospects for the use of porous permeable incubators made of titanium nickelide as effective carriers of bone marrow cells, liver and pancreatic cells. The processes of development of various types of tissues (mesenchymal, hepatic, pancreatic) in the intraporal system of titanium nickelide incubators are described. Experimental studies of methods of treating pathologies of the body with the use of new cellular technologies are presented. Positive effects have been shown in the treatment of tumor growth, toxic hepatitis and alloxan diabetes. The book is of interest to researchers, postgraduates, doctors and students in the field of pathophysiology, biotechnology, as well as for specialists working in the field of regenerative medicine and medical materials science.
55. Д10-15/33518
Физика и химия биолюминесценции : учебное пособие / В. С. Бондарь [и др.] ; под редакцией О. Шимомура, И. И. Гительзон ; Сибирский федеральный унниверситет, Институт фундаментальной биологии и биотехнологии. – 2-е изд., перераб. и доп. – Красноярск : СФУ, 2015. – 265 с. : ил. – (Биология). – Авт. указ. на обороте тит. л. – Парал. тит. л. англ. – Библиогр. : с. 253-265 (92 назв.). – ISBN 978-5-7638-3217-4. – Текст : непосредственный.
Abstract: The textbook discusses the ecology and basic properties of luminous bacteria, the structure of their bioluminescent system, the kinetics of the bioluminescent reaction, the mechanisms of the formation of excited states, the variety and application of bioluminescent systems using celenterazine or its analogues as a substrate.
56. Ар19-6503
Чжу Сяоминь
Создание микрокапсул путем самосборки и самоадаптации макромолекулярных систем : специальность 02.00.06 – высокомолекулярные соединения : автореферат диссертации на соискание ученой степени доктора химических наук / Чжу Сяоминь ; DWI – Лейбниц-институт интерактивных материалов. – Москва, 2019. – 48 с. : ил. – Библиогр. : с. 45-48 (30 назв.). – Текст : непосредственный.
57. R/18331/110/A
Advances in protein chemistry and structural biology. – Cambridge, MA [etc.] : Academic press : Elsevier, 20 – . – ISSN 1876-1623. – Текст : непосредственный.
Vol. 110 : Protein-protein interactions in human disease, pt. A / edited by Rossen Doney. – 2018. – 275 p. : ill. – Библиогр. в конце ст. – ISBN 978-0-12-814344-5.
Abstract: Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein interaction network as a means to not only identify the critical proteins involved in the etiology of human diseases, but also identify new protein targets for drug development. Sections cover such topics as protein-protein interaction modulators for epigenetic therapies, intrinsic disorder, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics of occupational diseases, and computational methods in predicting the impact of SNPs in protein-protein network, amongst other topics.
58. R/18331/111/B
Advances in protein chemistry and structural biology. – Cambridge, MA [etc.] : Academic press : Elsevier, 20 – . – ISSN 1876-1623. – Текст : непосредственный.
Vol. 111 : Protein-protein interactions in human disease, pt. B / edited by Rossen Doney. – 2018. – 282 p. – Библиогр. в конце ст. – ISBN 978-0-12-814342-1.
Abstract: Protein-Protein Interactions in Human Disease, Volume 111, Part B, promotes further research and development in the protein interaction network in order to identify critical proteins involved in the etiology of human diseases and locate new protein targets for drug development. Thus, this volume is of considerable interest to protein chemists, pharmacologists, cell biologists, immunologists, structural biologists, computational biochemists and other researchers working in the field. In addition, these articles would be of great benefit to medical, biology and pharmacology students who specialize in this field.
59. vr=A600591
Artificial Cells, Blood Substitutes, and Biotechnology : An International Journal. – Electronic text data. – London : Taylor and Francis Ltd, 1973 – . – Выходит раз в два месяца. – ISSN 1073-1199. – Режим доступа : http://www.informaworld.com/smpp/home~db=all (database website Informaworld) (дата обращения 29.11.21).
Abstract: Articles on research and development at four structural levels: molecules, cells, tissues and organs (corresponding to the principle of an integrated approach based on the integration of biotechnology, nanotechnology, molecular biology, bioencapsulation, polymer chemistry, engineering, medicine) aimed at the development of artificial cells, tissue engineering, artificial organs, blood substitutes, gene and cell therapy, gene and drug delivery systems, nanosensors, nanodevices, their clinical and industrial applications.
60. W5065
Biochimie. – Выходит ежемесячно. – ISSN 0300-9084.
Abstract: Articles and reviews based on research results in all sections of biology (enzymology, genetics, immunology, microbiology, macromolecule structure, etc.), provided that they are carried out by methods based on biochemistry, biophysics or molecular biology. Data on nucleotide sequences are involved. Individual rooms are themed. The last issue of the volume contains annual indexes of authors and articles systematized by keywords.
61. Biotechnology of hairy root systems / ed. P. M. Doran. – Electronic text data. – Berlin [etc.] : Springer, 2013. – 159 p. – (Advances in biochemical engineering/biotechnology , ISSN 0724-6145 ; vol. 134). – Загл. с экрана. – ISBN 978-3-642-39019-7. – URL: http://link.springer.com/book/10.1007/978-3-642-39019-7 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: Victor P. Bulgakov, Yuri N. Shkryl, Galina N. Veremeichik, Tatiana Y. Gorpenchenko and Yuliya V. Vereshchagina: Recent Advances in the Understanding of Agrobacterium rhizogenes-Derived Genes and Their Effects on Stress Resistance and Plant Metabolism. Le Zhao, Guy W. Sander and Jacqueline V. Shanks: Perspectives of the Metabolic Engineering of Terpenoid Indole Alkaloids in Catharanthus roseus Hairy Roots. Jian Wen Wang and Jian Yong Wu: Effective Elicitors and Process Strategies for Enhancement of Secondary Metabolite Production in Hairy Root Cultures. Amanda R. Stiles and Chun-Zhao Liu: Hairy Root Culture: Bioreactor Design and Process Intensification. Marina Skarjinskaia, Karen Ruby, Adriana Araujo, Karina Taylor, Vengadesan Gopalasamy-Raju, Konstantin Musiychuk, Jessica A. Chichester, Gene A. Palmer, Patricia de la Rosa, Vadim Mett, Natalia Ugulava, Stephen J. Streatfield and Vidadi Yusibov: Hairy Roots as a Vaccine Production and Delivery System. Zahwa Al-Shalabi and Pauline M. Doran: Metal Uptake and Nanoparticle Synthesis in Hairy Root Cultures.
62. Biotechnology Progress. – Electronic text data. – Malden, MA : John Wiley & Sons, Inc. – Выходит раз в два месяца. – ISSN 8756-7938. – URL: https://aiche.onlinelibrary.wiley.com/loi/15206033 (дата обращения 15.12.21). – Access mode : for authorization. users.
Abstract: Biotechnology Progress, an official, bimonthly publication of the American Institute of Chemical Engineers and its technological community, the Society for Biological Engineering, features peer-reviewed research articles, reviews, and descriptions of emerging techniques for the development and design of new processes, products, and devices for the biotechnology, biopharmaceutical and bioprocess industries. Widespread interest includes application of biological and engineering principles in fields such as applied cellular physiology and metabolic engineering, biocatalysis and bioreactor design, bioseparations and downstream processing, cell culture and tissue engineering, biosensors and process control, bioinformatics and systems biology, biomaterials and artificial organs, stem cell biology and genetics, and plant biology and food science. Manuscripts concerning the design of related processes, products, or devices are also encouraged. Four types of manuscripts are printed in the Journal: Research Papers, Topical or Review Papers, Letters to the Editor, and R & D Notes. Research articles are assigned to the following topical areas: Applied Cellular Physiology and Metabolic Engineering, Biocatalysts and Bioreactor Design, Bioseparations and Downstream Processing, Cell Culture and Tissue Engineering, Formulation and Engineering of Biomaterials, Process Sensing and Control.
63. Buselmaier, W.
Humangenetik fur Biologen / W. Buselmaier, G. Tariverdian ; SpringerLink (Online service). – Electronic text data. – Berlin ; Heidelberg : Springer, 2006. – 420 p. – (Springer-Lehrbuch, ISSN 0937-7433). – ISBN 978-3-540-29479-1. – URL: http://dx.doi.org/10.1007/3-540-29479-1 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: Im Zentrum dieses Lehrbuchs steht die moderne molekularbiologische Entwicklung. Sie besitzt das innovativste Potential innerhalb aller Forschungsgebiete. Neben verschiedenen methodischen Ansätzen präsentieren die Autoren die Ergebnisse des Human Genom Projekts, welches man wohl als das ehrgeizigste Wissenschaftsprojekt der Menschheitsgeschichte bezeichnen kann. Weitere Schwerpunkte sind: Das Methodeninventar der molekularen Humangenetik, Experimentelle Ansätze zur genetischen Manipulation, Klassische Genetik und Zytogenetik, Gene und Krebs, Klinische Genetik, DNA-Profile zur Individualidentifizierung, Die Evolution des Menschen – der molekularbiologische Ansatz, Populationsgenetik, Genetik und Umwelt.
64. vr=C549577
Cellular <and >Molecular Life Sciences. – Electronic text data. – Berlin : Springer Science+Business Media, 1997 – . – ISSN 1420-682X. – Режим доступа : https://www.springer.com/journal/18 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: The multidisciplinary journal Celluar and Molecular Life Sciences (CMLS) publishes research articles, mini-reviews, reviews, multi-author reviews and visions & reflections articles covering the latest aspects of biological and biomedical research. The journal will consider contributions focusing on molecular and cellular aspects of biomedicine, cell biology, immunology, molecular genetics, neuroscience, biochemistry, pharmacology and physiology related to pharmacology. In addition, CMLS welcomes comments on any article published in CMLS. Статьи, комментарии к статьям и обзоры новых исследований в области биологии и биомедицины: клеточные и молекулярные аспекты биомедицины, биология клетки, иммунология, молекулярная генетика, нейробиология, биохимия, фармакология.
65. Engineering in Translational Medicine. Vol. 1 / ed. W. Cai. – Electronic text data. – London : Springer-Verl., 2014. – 999 p. – ISBN 978-1-4471-4372-7. – URL: https://link.springer.com/book/10.1007%2F978-1-4471-4372-7 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: This book covers a broad area of engineering research in translational medicine. Leaders in academic institutions around the world contributed focused chapters on a broad array of topics such as: cell and tissue engineering (6 chapters), genetic and protein engineering (10 chapters), nanoengineering (10 chapters), biomedical instrumentation (4 chapters), and theranostics and other novel approaches (4 chapters). Each chapter is a stand-alone review that summarizes the state-of-the-art of the specific research area.
66. R/17669/7341
Forschungszentrum (Karlsruhe).
Wissenschaftliche Berichte : дис. ... / FZKA. – Karlsruhe : [s. n.], 19 – . – ISSN 0947-8620. – Текст : непосредственный.
7341 : Phylogenomic and functional analyses of enhancer evolution of sonic hedgehog paralogs : diss. / Y. Hadzhiev. – Karlsruhe : [s. n.], 2007. – IV, 90 p. : ill. – Рез. нем. – Библиогр. : с. 77-90.
Abstract: By functional analysis of shh paralog enhancers a reconstruction model for enhancer divergence during vertebrate evolution was developed. Our model suggests that the identified motifs of the ar-C enhancer function as binary switches responsible for specific activity between midline tissues and that these motifs are adjusted during functional diversification of paralogs. The unravelled motif changes can also account for the complex interpretation of activator and repressor input signals within a single enhancer.
67. International Conference on Biomedical Engineering (15 ; 2013 ; Singapore).
<The >15th International Conference on Biomedical Engineering : ICBME 2013, 4th to 7th December 2013, Singapore : Conference proceedings / ed. J. Goh. – Electronic text data. – Cham : Springer, 2014. – 968 p. – (IFMBE Proceedings, ISSN 1433-9277 ; vol. 43). – Загл. с экрана. – ISBN 978-3-319-02913-9. – URL: https://link.springer.com/book/10.1007/978-3-319-02913-9 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: This volume presents the proceedings of the 15th ICMBE held from 4th to 7th December 2013, Singapore. Biomedical engineering is applied in most aspects of our healthcare ecosystem. From electronic health records to diagnostic tools to therapeutic, rehabilitative and regenerative treatments, the work of biomedical engineers is evident. Biomedical engineers work at the intersection of engineering, life sciences and healthcare. The engineers would use principles from applied science including mechanical, electrical, chemical and computer engineering together with physical sciences including physics, chemistry and mathematics to apply them to biology and medicine. Applying such concepts to the human body is very much the same concepts that go into building and programming a machine. The goal is to better understand, replace or fix a target system to ultimately improve the quality of healthcare. With this understanding, the conference proceedings offer a single platform for individuals and organisations working in the biomedical engineering related field to gather and network with each other in so doing create the catalyst for future development of biomedical engineering in Asia.
68. Interplay between metal ions and nucleic acids / ed. A. Sigel [et al.]. – Electronic text data. – Dordrecht [etc.] : Springer, 2012. – 353 p. – (Metal ions in life sciences, – ISSN 1559-0836. – vol. 10). – Загл. с экрана. – ISBN 978-94-007-2172-2. – URL: http://link.springer.com/book/10.1007/978-94-007-2172-2 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: The Metal Ions in Life Sciences series links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes. The series reflects the interdisciplinary nature of Biological Inorganic Chemistry and coordinates the efforts of scientists in fields like biochemistry, inorganic and coordination chemistry, molecular and structural biology, enzymology, environmental chemistry, physiology, toxicology, biophysics, pharmacy, and medicine. Consequently, the volumes are an essential source for researchers active in these and related fields as well as teachers preparing courses, e.g., in Bioinorganic Chemistry. MILS-10: Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.
69. vr=N642366
Nature Methods. – Electronic text data. – [Б. м.] : Nature Publ. Group, 2004 – . – Загл. с титул. экрана. – Выходит ежемесячно. – ISSN 1548-7091. – Режим доступа : http://www.nature.com/nmeth/index.html (journal link) (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: Articles and reviews of the latest achievements in the development of new methods (with their detailed description) and significant improvements in the methods of samples and tests for laboratory practice in the field of biological and biomedical sciences and in related fields of chemistry, including for industrial laboratory research: chemical-biological methods (including chemical labeling, etc.); biophysical methods (including single molecule technology and "laboratory on a chip"); imaging technologies (including labeling methods, microscopy, optical spectroscopy and techniques of in vivo imaging); methods of manipulations with cell culture, incl. stem cells, as well as DNA cloning methods, proteomics methods (including separation, chromatography, mass spectrometry, display on the screen), protein engineering, etc.
70. R/17669/6855
Wissenschaftliche Berichte : дис. ... / FZKA. – Karlsruhe : [s. n.]. – ISSN 0947-8620. – Текст : непосредственный.
6855 : Charakterisierung des Transkriptionsfaktors SIX2 und seiner Bindungsstellen im GDNF- und Six2-Promotor : Diss. / S.Brodbeck. – Karlsruhe : [s. n.], 2003. – 117 S. : Ill. – Парал. загл. англ. Рез. англ. – Библиогр. : с.113-117.
Abstract: Ein Ziel dieser Arbeit war es, Faktoren zu identifizieren, die direkt an der Expression von GDNF beteiligt sind. In dieser Arbeit gelang es nachzuweisen, dass im C-Terminus des SIX2-Proteines eine Transaktivierungsdomäne lokalisiert ist. Auch konnte gezeigt werden, dass andere Six-Familienmitglieder dazu in der Lage sind, den Six2-Promotor zu aktivieren und eine Interaktion mit Pax-Familienmitgliedern wahrscheinlich ist.
71. Yu-Chen Hu
Gene Therapy for Cartilage and Bone Tissue Engineering / Yu-Chen Hu. – Electronic text data. – Berlin ; Heidelberg : Springer, 2014. – 89 p. – (SpringerBriefs in Bioengineering, ISSN 2193-0988). – Загл. с экрана. – ISBN 978-3-642-53923-7. – URL: https://link.springer.com/book/10.1007/978-3-642-53923-7#authorsandaffiliationsbook (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: "Gene Therapy for Cartilage and Bone Tissue Engineering" outlines the tissue engineering and possible applications of gene therapy in the field of biomedical engineering as well as basic principles of gene therapy, vectors and gene delivery, specifically for cartilage and bone engineering. It is intended for tissue engineers, cell therapists, regenerative medicine scientists and engineers, gene therapist and virologists. Dr. Yu-Chen Hu is a Distinguished Professor at the Department of Chemical Engineering, National Tsing Hua University and has received the Outstanding Research Award (National Science Council), Asia Research Award (Society of Chemical Engineers, Japan), and Professor Tsai-Teh Lai Award (Taiwan Institute of Chemical Engineers). He is also a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and a member of the Tissue Engineering International & Regenerative Medicine Society (TERMIS)-Asia Pacific Council.
Medications. Pharmaceutical biotechnology
72. Н/15730/191
Актуальные аспекты химической технологии биологически активных веществ : сборник научных трудов. – Москва : РХТУ им. Д. И. Менделеева, 20 – . – В надзаг. также: М-во науки и высш. образования Рос. Федерации. – Текст : непосредственный.
Вып. 191 / редакционная коллегия: Коваленко А. Е. [и др.]. – 2020. – 247 с. : ил. – Библиогр. в конце ст. – ISBN 978-5-7237-1756-5.
Abstract: The collection consists of the original abstracts of the conference reports of a theoretical and experimental nature, reflecting the results of research in the field of technology for obtaining new biomedical drugs, as well as determining the main analytical tasks and methods for determining narcotic, psychotropic and new doping agents in various matrices.
73. Ж2-11/57869
Актуальные проблемы науки фармацевтических и медицинских вузов: от разработки до коммерциализации : материалы научно-практической конференции с международным участием, посвященной 75-летию Пермской государственной фармацевтической академии (7-9 дек. 2011 г., Пермь) / под редакцией Т. Ф. Одеговой ; Перм. гос. фармацевт. акад. – Пермь : ПГФА, 2011. – 349 с. : ил. – Библиогр. в конце ст. – Текст : непосредственный.
Abstract: Materials of the scientific and practical conference with international participation dedicated to the 75th anniversary of the Perm State Pharmaceutical Academy. Conference topics: planning, innovation, quality management system; modern technologies for the creation of medicines: synthesis, pharmacological screening, preclinical and clinical studies, analysis, dosage forms; research in the field of medicinal plant raw materials; production of high-tech pharmaceutical substances and medicines in accordance with international standards; training of highly qualified personnel.
74. Д8-91/1311
Биотехнология лекарственных средств : учебное пособие / Александрова И. В., Бачина Т. А., Бойков С. В. [и др.]; под редакцией: Быкова В. А., Далина М. В. – Москва : [б. и.], 1991. – 303 с. : ил. – Сост. указ. на обороте обл. – В надзаг. : Моск. мед. акад. им. И. М. Сеченова. – Библиогр. : с. 301-302 (33 назв.). – Текст : непосредственный.
75. Д10-19/60495
Биофармация, или основы фармацевтической разработки, производства и обоснования дизайна лекарственных форм : учебное пособие / И. И. Краснюк [и др.] ; Первый Московский государственный медицинский университет имени И. М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет). – Москва : ГЭОТАР-Медиа, 2019. – 184, [2] с. : ил. – Библиогр. : с. 186 (12 назв.). – ISBN 978-5-9704-4710-9. – Текст : непосредственный.
Abstract: The textbook examines the biopharmaceutical foundations of pharmaceutical development and production of finished dosage forms, reveals the importance of pharmaceutical factors in ensuring the therapeutic efficacy and safety of medicines.
76. Д10-20/79900
Блынская, Е. В.
Методологические аспекты фармацевтической разработки инновационных лекарственных препаратов : монография / Е. В. Блынская, К. В. Алексеев. – Москва : Миттель Пресс, 2020. – 268 с. : ил. – Библиогр. : с. 229-268 (484 назв.). – ISBN 978-5-6044746-4-8. – Текст : непосредственный.
Abstract: The monograph describes the principles of the modern theory of innovation, methodological foundations for the creation of innovative medicines based on the biopharmaceutical classification system. Special attention is paid to biopharmaceutical aspects of the development of modified-release dosage forms, the key stages of optimization of the technological process are outlined. Examples of formulations and technologies of innovative medicines are given.
77. Ж2-17/62728
Гунар, О. В.
Основы валидации микробиологических методик фармацевтического анализа : учебное пособие / О. В. Гунар, Н. Г. Сахно, Р. А. Абрамович. – Москва : Рос. ун-т дружбы народов, 2017. – 221 с. : ил. – Библиогр. : с. 193-209 (266 назв.). – ISBN 978-5-209-07471-7. – Текст : непосредственный.
Abstract: The manual highlights topical issues related to the validation of microbiological techniques used in pharmaceutical production, in expert, control, research and other institutions. The approaches described in modern Russian and foreign scientific literature and regulatory documentation are summarized. The data on the main stages and directions of validation, estimated parameters and criteria for the acceptability of the results are analyzed. The authors' own validation studies performed using modern statistical evaluation methods, computer programs and information technologies are presented. The types of alternative microbiological methods of pharmaceutical analysis are considered, and practical aspects of their application are shown. The publication is intended for specialists in the field of pharmaceutical microbiology and represents a certain experience in the application of validation procedures in the work of the microbiology laboratory.
78. Ар19-5299
Есипов, Р. С.
Методология биотехнологического получения рекомбинантных пептидов медицинского назначения : специальность 03.01.06 – Биотехнология (в том числе и бионанотехнологии) : автореферат диссертации на соискание ученой степени доктора химических наук / Р. С. Есипов ; Институт биоорганической химии им. М. М. Шемякина и Ю. А. Овчинникова Российской академии наук. – Москва, 2019. – 55 с. : ил. – Библиогр. : с. 48-55. – Текст : непосредственный.
79. Д10-19/67483
Задачник по ИК- и ЯМР-спектроскопии лекарственных препаратов и биологически активных соединений : учебное пособие / А. А. Бакибаев, С. Ю. Паньшина, О. В. Пономаренко [и др.] ; Министерство науки и высшего образования Российской Федерации, Национальный исследовательский Томский государственный университет. – Томск : Издательский дом Томского гос. ун-та, 2019. – 123 с. : ил. – Авт. на обл. не указ. – Библиогр. : с. 110-111 (21 назв.). – ISBN 978-5-94621-810-8. – Текст : непосредственный.
Abstract: The manual allows you to get acquainted with the methods of IR and NMR spectroscopy by solving structural problems of identifying drugs and biologically active compounds, contributes to the formation of the ability to analyze the data of spectra. The manual is intended for undergraduates studying under the Autonomous Master's Program "Translational chemical and Biomedical Technologies", and for undergraduates and postgraduates specializing in the analysis of drugs and biologically active compounds.
80. Ар19-8822
Калинин, С. А.
Дизайн и синтез изоформно-селективных ингибиторов карбоангидразы человека для биомедицинских приложений : специальность 02.00.16 – Медицинская химия : автореферат диссертации на соискание ученой степени кандидата химических наук / С. А. Калинин. – Черноголовка, 2019. – 26 с. : ил. – Библиогр. : с. 25-26 (16 назв.). – Текст : непосредственный.
81. Ар16-10794
Ковалева, Е. В.
Разработка и применение методов ПЦР и ИФА для анализа остаточных ДНК и белков штаммов-продуцентов в биофармацевтических субстанциях : специальность 03.01.06 : автореферат диссертации на соискание ученой степени кандидата химических наук / Е. В. Ковалева. – Москва, 2016. – 26 с. : ил. – Библиогр. : с. 25-26. – Текст : непосредственный.
82. Ар18-13
Ковальский, И. В.
Стандартизация методов контроля качества вирусвакцины против ньюкаслской болезни птиц с применением статистических универсальных программных пакетов : специальность 03.01.06 : автореферат диссертации на соискание ученой степени кандидита технических наук / И. В. Ковальский. – Щелково, 2018. – 24 с. : ил. – Библиогр. : с. 22-24 (13 назв.). – Текст : непосредственный.
83. Ар10-27293
Кононова, Н. В.
Разработка промышленных технологий очистки рекомбинантных белков: гормона роста человека и гранулоцитарного колониестимулирующего фактора : специальность 03.01.06, 02.00.10 : автореферат диссертации на соискание ученой степени кандидата химических наук / Н. В. Кононова. – Москва, 2010. – 24 с. : ил. – Библиогр. : с. 24 (5 назв.). – Текст : непосредственный.
84. Ар12-22614
Малашенко, Е. А.
Изучение сравнительной кинетики растворения по процедуре "биовейер" воспроизведенных лекарственных средств I класса биофармацевтической классификационной системы : специальность14.04.02 : автореферат диссертации на соискание ученой степени кандидата фармацевтических наук / Е. А. Малашенко. – Москва, 2012. – 26 с. : ил. – Библиогр. : с. 25-26 (11 назв.). – Текст : непосредственный.
85. Н/19860/2
Международная научная школа для молодежи "Школа научно-технического творчества и концептуального проектирования". Региональная научно-практическая конференция "Исследования молодых ученых – вклад в инновационное развитие России". – Астрахань : [б. и.], 2011 – . – В надзаг. : Федерал. целевая программа "Научные и научно-педагогические кадры инновационной России", Фонд содействия развитию малых форм предприятий в научно-технической сфере. – Текст : непосредственный.
Т. 2 : Биотехнология. Медицина и фармакология. Химия, новые материалы, химические технологии. – 2011. – 383 с. : ил. – Библиогр. в конце отд. ст. – ISBN 978-5-9926-0523-5. – ISBN 978-5-9926-0524-2.
Abstract: The collection contains materials and abstracts of reports in the areas of "Biotechnology", "Medicine and Pharmacology" and "Chemistry, new materials and chemical technologies".
86. Д9-13/95181
Орехов, С. Н.
Фармацевтическая биотехнология : руководство к практическим занятиям: учебное пособие / С. Н. Орехов; под редакцией В. А. Быкова, А. В. Катлинского. – Москва : ГЭОТАР-Медиа, 2013. – 381 с. – Библиогр. : с. 378-379. – Предм. указ.: с.380-381. – ISBN 978-5-9704-2499-5. – Текст : непосредственный.
Abstract: The textbook provides information about modern methods of obtaining medicines in the conditions of industrial biopharmaceutical production. The greatest attention is paid to biotechnological aspects of antibiotic production. The methods of isolation of antibiotic-producing microorganisms from the soil, their identification by cultural and morphological characteristics and storage of producing microorganisms are described in detail. Microbiological methods for determining the sensitivity and concentration of antibiotics are presented. Information is given on the industrial production of drugs of various pharmacological groups (vitamins and coenzymes, amino acids, steroid hormones, etc.) using biotechnology. Examples of obtaining recombinant structures in laboratory conditions are shown. Technological techniques used to assess the quality of finished vaccines are considered, data on microbial biotechnology are presented, material on probiotics, their properties and biotechnological potential of probiotic microorganisms is presented, their importance for human health is shown. The textbook contains all the necessary program materials for the course of pharmaceutical biotechnology by students of medical universities. To facilitate the assimilation of the material, the manual contains a reference dictionary with comments.
87. Ар20-1530
Орлова, О. И.
Хроматомасс-спектрометрическое определение аддуктов алкилирующих агентов с ДНК и ацетилцистеином в биопробах : специальность 02.00.02 – Аналитическая химия : автореферат диссертации на соискание учёной степени кандидата химических наук / Орлова Ольга Игоревна. – Санкт-Петербург, 2020. – 23 с. : ил. – Библиогр. : с. 22-23 (15 назв.). – Текст : непосредственный.
88. Д7-90/86880
Перспективы создания лекарственных средств методами биологического и химического синтеза : сборник научных трудов / Всесоюзный научно-исследовательский технологический институт антибиотиков и ферментов медицинского назначения ; редакционная коллегия: Б. В. Москвичев (гл. ред.) [и др.]. – Москва : ВНИТИАФ, 1990. – 238 с. : ил. – Библиогр. в конце ст. – Текст : непосредственный.
Abstract: The collection presents research materials on the creation of medicines by methods of biological and chemical synthesis. Some features of the creation of new antibiotics, enzyme preparations, drugs of nucleoside nature are shown. The results characterizing drugs of the following therapeutic groups are presented: antibiotics, enzyme preparations for the treatment of digestive insufficiency, wound-healing anti-inflammatory drugs, drugs for the treatment of heart and vascular diseases, immunostimulants.
89. Решетникова О. В.
Биотехнологические особенности получения антибиотиков / О. В. Решетникова, А. А. Рутенбург. – Текст электронный // Актуальные вопросы теории и практики современной биотехнологии: сборник трудов конференции, 15 сентября 2015 года, Ленинградский государственный университет им. А.С. Пушкина. – Санкт-Петербург, г. Пушкин : Издательство Ленинградский государственный университет имени А.С. Пушкина (Санкт-Петербург), 2015. – С. 149-155. – URL: https://www.elibrary.ru/item.asp?id=27476452 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: The synthesis of antibiotics is a specific metabolic process that has arisen and is fixed in the process of the evolution of microorganisms. The article describes the characteristics of antibiotics, describes their use, biotechnological methods of increasing the productivity of microorganisms and obtaining antibiotics.
90. Ар13-1144
Санарова, Е. В.
Создание и биофармацевтическое изучение новой липосомальной лекарственной формы тиосенса для фотодинамической терапии : специальность 14.04.01 : автореферат дисссертации на соискание ученой степени кандидата фармацевтических наук / Е. В. Санарова. – Москва, 2012. – 24 с. : ил. – Библиогр. : с. 22-24 (24 назв.). – Текст : непосредственный.
91. Д10-21/80627
Станишевский, Я. М.
Промышленная биотехнология лекарственных средств : учебное пособие / Я. М. Станишевский ; Министерство науки и высшего образования РФ. – Москва : ГЭОТАР-Медиа, 2021. – 142 с. : ил. – Библиогр. : с. 139 (10 назв.). – Предм. указ. : с. 140-142. – Факт. дата выхода кн. – 2020 г. – ISBN 978-5-9704-5845-7. – Текст : непосредственный.
Abstract: The textbook outlines the main stages, methods and processes of biotechnological production of medicines. The main achievements of microbial biotechnology and engineering enzymology in the creation of medicinal, preventive and diagnostic drugs are considered. An overview of current developments in biotechnological production in the field of obtaining vaccines, bacteriophages, bacterial preparations that normalize the human microflora, antibiotics, vitamins and enzyme preparations is given.
92. Ар16-8095
Ульянова, Н. Ю.
Синтез, исследование каталитической и биологической активности цеолитов со структурами Rho, Beta и паулингита, модифицированных наночастицами и кластерами серебра : специальность 02.00.04 : автореферат диссертации на соискание ученой степени кандидата химических наук / Н. Ю. Ульянова. – Санкт-Петербург, 2016. – 23 с. : ил. – Библиогр. : с. 21-23 (13 назв.). – Текст : непосредственный.
93. Д7-90/85967
Успехи в области изучения и производства антибиотиков. Проблемы биотехнологии физиологически активных веществ : труды Всесоюзного научно-исследовательского института антибиотиков ; редакционная коллегия: С. М. Навашин (главный редактор) [и др.] – Москва : [б. и.], 1990. – 147 c. : ил. – Библиогр. в конце ст. – Текст : непосредственный.
Abstract: The results of experimental studies of biotechnological processes of physiologically active substances are presented. Methods for determining the activity of antibiotics, including bioluminescent methods; processes of antibiotic biosynthesis; enzyme immunoassay system and its use for the determination of physiologically active substances; catalytic and physico-chemical properties of enzymes; the effect of α- and γ-interferons on sensitivity reactions.
94. Ж2-03/31187
Фармацевтическая микробиология / В. А. Галынкин, Н. А. Заикина, В. И. Кочеровец, Т. С. Потехина. – Москва : Арнебия, 2003. – 351 с. – В надзаг. : С.-Петербург. гос. химико-фармацевт. акад. – Библиогр. : с. 312-313. – ISBN 5-9244-0020-4. – Текст : непосредственный.
Abstract: Modern information about microorganisms - producers of BAS, contaminants of pharmaceutical production, pathogens of infectious diseases, as well as about biocidal agents, chemotherapeutic substances and antiseptics, the mechanism of their action and problems of microbial resistance are presented in the light of the applicability of this knowledge for specialists in the field of industrial production, pharmacy manufacturing, quality control and use of medicines.
95. Д10-15/23087
Фармакологическая наука – от теории к практике : материалы II Всероссийской научной Интернет-конференции с международным участием, 3 марта 2015 года / Д. Н Синяев. – Казань :., 2015. – 43 с. : ил. – Библиогр. в конце отд. ст. – ISBN 978-5-906217-78-3. – Текст : непосредственный.
Abstract: The scientific publication was compiled following the results of the correspondence scientific and practical conference with international participation "Pharmaceutical Sciences: from theory to practice", held on November 25, 2016 at the Federal State Budgetary Educational Institution of Higher Education "Astrakhan State Medical University" of the Ministry of Health of the Russian Federation.
96. АР00-6619
Шикова, Ю. В.
Разработка состава, технологии и биофармацевтические исследования лекарственных форм с дибунолом : специальность 15.00.01 : автореферат диссертации на соискание ученой степени канд. фармацевт. наук / Ю. В. Шикова. – Москва : [б. и.], 1999. – 25 с. : ил. – Библиогр. : с. 23-24 (14 назв.). – Текст : непосредственный.
97. Ж2-10/49054
Шимановский, Н. Л.
Молекулярная и нанофармакология / Н. Л. Шимановский, М. А. Епинетов, М. Я. Мельников. – Москва : Физматлит, 2010. – 623 с. : ил. – Библиогр. в конце глав. – ISBN 978-5-9221-1208-6. – Текст : непосредственный.
Abstract: The information about the chemical structure, molecular mechanism of action and biotransport of various groups of medicinal substances is presented. The book summarizes the results of the development of pharmacology in recent years, which became possible thanks to the fundamental achievements of molecular biology, biochemistry, biophysics, biocybernetics and nanotechnology. New data on the chemical structure, molecular mechanisms of action and biotransport of various groups of medicinal substances are presented. Modern information about the molecular pharmacology of mediator and receptor systems is presented, mathematical models of pharmacokinetics and pharmacodynamics of physiologically active substances of various types are presented. The ways of searching for new medicines based on a comprehensive study of the mechanisms of functioning of living systems are described. The prospects of using nanotechnology in the creation of new drugs with a more selective effect, fundamentally new substances with directed transport, complex drugs capable of simultaneously visualizing pathological foci and providing a local therapeutic effect are considered.
98. Д9-09/61161
Ярыгина, Т. И.
Новые биологически активные производные ГАМК: физико-химические свойства и методы контроля качества / Т. И. Ярыгина, В. А. Дубовик, Г. П. Вдовина. – Пермь : ПГФА "Росздрава", 2009 (Пермь). – 122 с. : ил. – Авт. указ. на обороте тит. л. – Библиогр. : с. 102-122. – В надзаг. : Перм. гос. фармацевтическая акад. Федерал. агентства по здравоохранению и социальному развитию. – ISBN 978-5-91247-032-5. – Текст : непосредственный.
99. R/18331/98
Advances in protein chemistry and structural biology / ed.: A. McPherson, D. S. Eisenberg. – Amsterdam [etc.] : Academic press: Elsevier, 20 – . – ISSN 1876-1623. – Текст : непосредственный.
Vol. 98 : Protein and Peptide Nanoparticles for Drug Delivery / ed. R. Donev. – 2015. – 369 p. : ill. – Библиогр. в конце разд. – Указ. в конце кн. – ISBN 978-0-12-802828-5.
Abstract: Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area. Chapters are written by authorities in their field. Targeted to a wide audience of researchers, specialists, and students.The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables. Researchers and specialists in protein structure and interactions, cancer biology, psychiatry and mass spectrometry. This volume would also be of a great use to students working on projects in these areas.
100. vr=M712149
Molecular Pharmaceutics. – Electronic text data. – Washington, DC : American Chemical Society, 2004 – . – n. – Выходит раз в два месяца. – ISSN 1543-8384. – Загл. с титул. экрана. – Режим доступа : http://pubs.acs.org/journal/mpohbp (journal link) (дата обращения 29.11.21).
Abstract: Articles, short articles, reports and critical reviews on theoretical and experimental research of pharmaceutical products at the molecular level by methods of physical and pharmaceutical chemistry, biochemistry and biophysics, molecular and cellular biology, polymer science and materials science aimed at creating drugs and effective systems for their delivery; descriptions of the research conducted on the discovery and development of new drugs and new types of drug carriers (study of nanoscale materials, distribution of nanoparticles, nanodrugs, multifunctional medical nanodevices, etc.).
101. Ozkan, S. A.
Electroanalysis in Biomedical and Pharmaceutical Sciences. Voltammetry, Amperometry, Biosensors, Applications / S. A. Ozkan, J. -M. Kauffmann, P. Zuman. – Electronic text data. – Berlin [etc.] : Springer-Verl., 2015. – 350 р. – (Monographs in Electrochemistry, ISSN 1865-1844). – Загл. с экрана. – ISBN 978-3-662-47138-8. – URL: https://link.springer.com/book/10.1007/978-3-662-47138-8 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: Through this monograph, the pharmaceutical chemist gets familiar with the possibilities electroanalytical methods offer for validated analyses of drug compounds and pharmaceuticals. The presentation focuses on the techniques most frequently used in practical applications, particularly voltammetry and polarography. The authors present the information in such a way that the reader can judge whether the application of such techniques offers advantages for solving a particular analytical problem. Basics of individual electroanalytical techniques are outlined using as simple language as possible, with a minimum of mathematical apparatus. For each electroanalytical technique, the physical and chemical processes as well as the instrumentation are described. The authors also cover procedures for the identification of electroactive groups and the chemical and electrochemical processes involved. Understanding the principles of such processes is essential for finding optimum analytical conditions in the most reliable way. Added to this is the validation of such analytical procedures. A particularly valuable feature of this book are extensive tables listing numerous validated examples of practical applications. Various Indices according to the drug type, the electroactive group, and the type of method as well as a subject and author index are also provided for easy reference.
102. Sterile filtration / ed. M. W. Jornitz. – Electronic text data. – Berlin ; Heidelberg : Springer , 2006. – 640 p. – (Advances in biochemical engineering/biotechnology, ISSN 0724-6145 ; 98). – ISBN 978-3-540-33018-9. – URL: http://dx.doi.org/10.1007/b101405 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: This book focuses on sterilizing grade filters in the biopharmaceutical industry, emphasizing practical applications of universal and dependable operational protocols, integrity testing, and troubleshooting to streamline the production and preparation of pharmaceuticals. Addresses the complexities of globalizing redundancy in filtration!
103. Vogt, C. H.
Erfolg strategischer F&E-Kooperationen : eine empirische Untersuchung mittels Patentdaten am Beispiel der Biopharmazie / C. H. Vogt. – Electronic text data. – Wiesbaden : Dt. Univ.-Verl., 2008. – 353 p. – ISBN 978-3-8350-5533-9. – URL: https://link.springer.com/book/10.1007/978-3-8350-5533-9 (дата обращения 29.11.21). – Access mode : for authorization. users.
Abstract: Forschungsintensive Industrien wie die Biotechnologie sind geprägt von einer Vielzahl an Kooperationen zwischen etablierten Großunternehmen mit kleinen Partnern. Aber die Misserfolgsraten solcher Vereinbarungen sind trotz einer zunehmenden Kooperationserfahrung der beteiligten Unternehmen sowie gestiegenen Investitionsvolumina weiterhin hoch und wesentliche Erfolgsfaktoren unbekannt. Carsten Hendrik Vogt identifiziert Erfolgsfaktoren für F&E-Kooperationen, analysiert Lerneffekte aus Kooperationen und entwickelt ein Modell, das zur Vorhersage der Erfolgswahrscheinlichkeit einer F&E-Kooperation in der Praxis eingesetzt werden kann. Für den Erfolg solcher Kooperationen spielen mehrdimensionale technologische Kompetenzen sowie die Fähigkeit, das Wissen des Kooperationspartners zu integrieren und in eigene Produkte umzusetzen eine wesentliche Rolle. Nur bei einem Vorhandensein der sog. Absorptive Capacity können etablierte Unternehmen eine langfristige Verbesserung ihres Technologieportfolios erzielen und am Markt führend agieren.
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